Figure 5. Intestinal villus microcirculation in (A) control animals and (B) normothermic animals subjected to intestinal ischemia after the administration of acridine orange. Few adherent leukocytes were observed within the villus microcirculation of control animals (arrows). Reperfusion of the small intestine induced the adherence of numerous leukocytes within the supplying arteriole and the capillaries. Control villi were associated with a thick epithelial layer of cells, whereas this healthy architecture was lost within 15 to 30 minutes of reperfusion in normothermic ischemia–reperfusion animals. Magnification ×590.