Figure 4. Figure 4. Cytotoxicity and anti-tumor activity of DF3γ34.5. (A) MUC1-negative cells (A375, Vero, and HUVEC) and MUC1-positive cells (MCF7, CAPAN2, and SW1990)were infected with increasing moi values of DF3γ34.5, MGH1, or hrR3. Cell survival was measured 6 days later. (B) CAPAN2 tumors growing on the flanks of BALB/c (nu/nu) mice were treated with a single intratumoral inoculation of 1 x 108 pfu DF3g34.5 or mock-infected media and tumor volumes were subsequently measured.