Table 1. CLINICAL AND BIOCHEMICAL DATA OF INDEX CASES AND PATIENTS AT RISK FOR MEN 2A/FMTC WHO INHERITED A CODON 790/791 MUTATION

ND, not determined; CEA, serum carcinoembryonic antigen concentration, normal <4 ng/mL; PTH, serum parathyroid hormone concentration, normal 10–72 pg/mL; Ca, serum calcium concentration, normal range; MTC, medullary thyroid carcinoma; CCH, C-cell hyperplasia.

Basal calcitonin level normal <20 pg/mL.

Index cases of the kindreds A–D are in bold.

Normal 2.08–2.60 mmol/L.