FIGURE 1. Decreased IFNγ and IL-2 expression in CD4⁺ and CD8⁺ T cells from trauma patients versus control subjects on day 1 after injury. (A and B) Decreased SEB-induced IFNγ and IL-2 but not IL-4 nor IL-10 intracellular expression in CD4⁺ and CD8⁺ T cells from patients, compared with control subjects. Data are expressed as the mean ± sem. *P < 0.05; ^†P < 0.001 for patients versus control subjects. (C and D) FACS plots of SEB-induced intracellular IFNγ expression and IgG isotype control in the gated T cell subsets. Results are representative of a trauma patient compared with a healthy control subject. The value shown in the upper right quadrant indicates the percentage of cytokine-positive cells.