Figure 5. ROS production in rotenone- and t-BHP-treated MT-overexpressing HeLa cells.
ROS production was measured in control (open bars), MT1B- (light grey bars) and MT2A- (dark grey bars) overexpressing cell lines treated with rotenone or t-BHP. Values, which were normalized to protein content, are means±S.D. (n=8) and expressed as percentage relative to untreated cells. *P<0.05 when compared with untreated cells of the same cell line; †P<0.05 when compared with control cell line at the same treatment; ‡P<0.05 when comparing MT2A- with MT1B-overexpressing cell line at the same treatment.