Boxplots of biases for the two estimators and . From a simulated population of N=4,000 haplotypes, 300 random samples of n haplotypes were drawn for n=50, 200, and 500. and were calculated for a particular marker pair located 5 kb apart. The six boxplots (from left to right) are for , , , , , and , where the numbers in the subscript denote the sample size, n.