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. 2006 Feb 13;78(4):615–628. doi: 10.1086/502632

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© 2006 by The American Society of Human Genetics. All rights reserved.

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LD measures for HapMap data for 56,001 SNPs on the X chromosomes of 30 women in the CEPH population. A, LD-decay rates at every SNP locus, estimated from polymorphic SNPs in the neighboring 100-kb region. B, Display with higher resolution for an arbitrarily selected region of 275 kb. C, Residual plot from fitting the linear-regression model with data from the 275-kb region. Adjacent marker pairs with large negative residuals are heuristically considered recombination hotspots and are plotted using colored dots, with red representing even more extreme residuals than blue. D–F, Pseudocolor images of pairwise |D^′|, r², and matrices. The red and blue dashed lines correspond to the marker pairs plotted using red and blue dots in panel C.

Inline graphic — LD measures for HapMap data for 56,001 SNPs on the X chromosomes of 30 women in the CEPH population. A, LD-decay rates at every SNP locus, estimated from polymorphic SNPs in the neighboring 100-kb region. B, Display with higher resolution for an arbitrarily selected region of 275 kb. C, Residual plot from fitting the linear-regression model with data from the 275-kb region. Adjacent marker pairs with large negative residuals are heuristically considered recombination hotspots and are plotted using colored dots, with red representing even more extreme residuals than blue. D–F, Pseudocolor images of pairwise |D^′|, r², and matrices. The red and blue dashed lines correspond to the marker pairs plotted using red and blue dots in panel C.