Table 4.

Caspase-12 Summary Statistics

	Sample characteristics				Allele frequency distribution tests				Haplotype tests
Location	Sample Size (Chromosomes)	Polymorphic Sites	Nucleotide Diversity (×104)	θ W (×104)	Tajima’s D	Fu and Li’s D	Fu and Li’s F	Fay and Wu’s H (P)	Fu’s Fs	Common Haplotype Frequency
Entire region (13.3 kb)
Whole	155	123	4.5	16.5	−2.32a	−2.75a	−3.06b	−46.2 (.002)b	−27.7b
African	52	99	9.1	16.5	−1.59a	−1.05	−1.54	−28.7 (.021)a	−5.8
European	50	7	.5	1.2	−1.57a	−1.17	−1.54	−.9 (.287)	−6.6b
Chinese	52	47	1.9	7.8	−2.60b	−3.20b	−3.59b	−33.5 (.000)b	−5.2
Active	8	61	19.7	17.7
Inactive (whole)	147	76	2.0	10.3
Inactive (African)	46	57	4.4	9.7
Inactive (non-African)	101	21	.7	3.0
LD block (8.6 kb)
Whole	155	90	4.5	18.2	−2.37b	−2.46a	−2.91b	−38.4 (.005)b	−18.5b	99b
African	52	71	9.1	17.9	−1.71a	−1.29	−1.77	−23.2 (.027)a	−2.9	21b
European	50	4	.3	1	−1.67a	−1.26	−1.63	.2 (.398)	−4.3a	43
Chinese	52	37	2.1	9.3	−2.62b	−3.16b	−3.58b	−25.1 (.000)b	−3.2	35b
Active	8	50	20.9	21.9
Inactive (all)	147	43	1.4	8.8
Inactive (African)	46	29	2.9	7.5
Inactive (non-African)	101	14	.6	3.1

^aP<.05.

^bP<.01 (one-sided tests).