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Expression of MAST205 decreased NHE3 activity in OK cells. A: OK cells were transfected with MAST205 or pcDNA3.1HisB as a control. Representative traces of Na-dependent pHi recovery are shown. Similar results obtained from 8 sets of experiments; each set consists of at least 3 cover slips studied. B: OK cells were transfected with pcDNA, MAST205, MΔ5, PC, or KMΔ5; n = 5. *P < 0.01 compared with pcDNA-transfected control. Results are presented as means (bars) and SD (error bars).
