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After LPS stimulation, NF-κB subunits bind to promoters that were previously bound by p50. Fraction of bound genes in activated cells that were prebound by p50 before stimulation at two significance levels, 0.002 (dark blue) and 0.01 (light blue). All NF-κB subunits bound to significant numbers of p50 target genes. In contrast, the binding pattern of E2F4 was not related to p50 binding and followed the pattern expected by chance (randomized data).
