TABLE 1.

Patient characteristics in population pharmacokinetic study of L-AmB^a

Variable	Mean (SD)	Median	Range
No. of patients	39
No. of courses	48
No. of observations	637
No. of observations/course	13.3 (7.0)	12	3-30
Sex (male/female)	26/13
Age, yr	7.1 (5.1)	6.5	0.17-17
Weight, kg	28.8 (19.8)	21.1	6.1-84.1
Height, cm	119.2 (33.7)	118.5	61.5-190.0
BSA, m2b	0.96 (0.46)	0.82	0.32-2.11
Creatinine, μmol · l−1	74 (108)	47	19-659
GGT, U · l−1c	105 (211)	39	11-1398

^aIn the cohort, 15 patients had been diagnosed with acute lymphoblastic leukemia, 4 had been diagnosed with acute myloid leukemia, and 20 had received other diagnoses. Sixteen patients had received bone marrow transplants (12 allogeneic and 4 autologous).

^bBSA, body surface area (18); BSA(m²) = .

^cGGT, gamma-glutamyl transferase.