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Effects of mefloquine on hyperactivity/anxiousness at various time points
| Time | Incidence (%) of hyperactivity/anxiousness in treatment groupa receiving:
|
||||
|---|---|---|---|---|---|
| Vehicle | Mefloquine dose (mg/kg)
|
||||
| 45 | 187 | 327 | 574 | ||
| Predose | 12.5 | 0 | 0 | 0 | 0 |
| 24 h | 12.5 | 0 | 25 | 50 | 50 |
| 48 h | 12.5 | 0 | 0 | 27.5 | 37.5 |
Each treatment group consisted of eight rats.
