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The region surrounding D88 in S12, as determined in the structure of the T. thermophilus 30S subunit complexed with antibiotics (7) (Protein Data Bank accession no. 1FJG). The conserved K42- and P90-containing loops of S12 are shown in blue. D88 is highlighted in red, P90 in yellow, K87 in green, and K42 in orange. The streptomycin (strep) binding site is proximal to these residues and is shown as tricolor sticks. This figure was illustrated with PyMol (9).
