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. 2006 Apr;50(4):1376–1383. doi: 10.1128/AAC.50.4.1376-1383.2006

TABLE 1.

PPI-0903, penicillin, cefotaxime, and methicillin in vitro activities against selected isolates of S. pneumoniae, S. aureus, and Enterobacteriaceae

Organism MIC (mg/liter)
PPI-0903 Penicillin Cefotaxime Methicillin
S. pneumoniae 10813 0.008 0.008 0.12
S. pneumoniae 1199 0.06 1.0 0.25
S. pneumoniae 1329 0.06 2.0 0.5
S. pneumoniae 1325 0.06 2.0 0.5
S. pneumoniae 1293 0.12 2.0 0.5
S. aureus 25923 0.12 0.5 0.25
S. aureus 29213 0.25 1.0 0.5
MRSA 0.50 8.0 >8.0
S. aureus 33591 1.0 >64 >8.0
E. coli 25922 1.0 0.03
E. coli 1894-1 2.0 0.03
K. pneumoniae 43816 2.0 0.03
K. pneumoniae 216 2.0 0.03