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FN-PAGE analysis of inhibition of 6-HB formation by PS-ONs. The 40-base Randomer 1 or 2 ONs (200 μM) were added to the N36 peptide (40 μM) before or after the addition of FITC-labeled C34 peptide (40 μM). The N36/FITC-C34 6-HB complex has a retarded mobility (as indicated on the right of the gel). Randomers 1 and 2 were active in preventing 6-HB formation when they were incubated with N36 prior to the addition of FITC-C34.
