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. 2006 Apr;50(4):1304–1310. doi: 10.1128/AAC.50.4.1304-1310.2006

FIG. 1.

FIG. 1.

Dosing schema. Day 1, administration of a single 1,000-mg dose of saquinavir mesylate (SQV) in the morning; day 2, coadministration of a single 300-mg dose of tenofovir DF (TDF) with a single 1,000-mg dose of SQV in the morning; days 3 to 8, administration of a single 300-mg dose of TDF once daily (QD) in the morning; day 9, coadministration of a single 300-mg dose of TDF and a single 1,000-mg dose of SQV in the morning; day 10, coadministration of a single 300-mg dose of TDF and a single 1,000/100-mg dose of ritonavir-boosted saquinavir (SQV/r) in the morning; days 11 to 24, coadministration of 1,000/100 mg of SQV/r twice daily (BID) in the morning and evening with a 300-mg dose of TDF QD in the morning; days 25 to 38, administration of 1,000/100 mg of SQV/r BID in the morning and evening; day 39, administration of a single 1,000/100-mg dose of SQV/r in the morning.