TABLE 1.
Summary of S strain deletions with reference to the M. avian subsp. paratuberculosis K10 genome
| S strain deletion | Start position | End position | Size (bp) | ORP(s) includeda | M. tuberculosis equivalent | M. avian subsp. paratuberculosis gene name | Putative functionb |
|---|---|---|---|---|---|---|---|
| 1 | 1625179 | 1633227 | 8,049 | Par MAP1484c | Rv3161c | Putative dioxygenases | |
| MAP1485c | Rv0214 | Acyl-CoA synthase | |||||
| MAP1486c | Rv0456c | Enoyl-CoA hydratase/isomerase superfamily | |||||
| MAP1487c | Rv2496c | Pyruvate dehydrogenase E1 component (beta) subunit | |||||
| MAP1488c | Rv2497c | Pyruvate dehydrogenase E1 component (alpha) subunit | |||||
| MAP1489c | Rv2750 | Putative dehydrogenase | |||||
| MAP1490 | Alpha-methylacyl-CoA racemase | ||||||
| Par MAP1491 | Alpha-methylacyl-CoA racemase | ||||||
| 2 | 1888735 | 1908664 | 19,930 | MAP1728c | yfnB | 2-Haloalkanoic acid dehalogenase | |
| MAP1729c | Rv2605c | Thioesterase II | |||||
| MAP1730c | Putative ATP/GTP-binding protein | ||||||
| MAP1731c | Hypothetical protein | ||||||
| MAP1732c | Rv0302 | Transcriptional regulator (TetR/AcrR family) | |||||
| MAP1733 | Proline-rich protein precursor | ||||||
| MAP1734 | Rv2123 | PPE family protein | |||||
| MAP1735 | Rv0217c | lipW_1 | Probable esterase | ||||
| MAP1736 | Putative tetR family transcriptional regulator | ||||||
| MAP1737 | Rv0677c | mmpS5 | Conserved small-membrane protein | ||||
| MAP1738 | Rv0676c | mmpL5 | Conserved large-membrane protein | ||||
| MAP1739c | Rv2002 | fabG3_1 | 3-Oxoacyl-(ACP) reductase | ||||
| MAP1740c | Rv3132c | Sensor histidine kinase | |||||
| MAP1741c | Rv2005c | Conserved hypothetical protein | |||||
| MAP1742c | Rv2026c | Conserved hypothetical protein | |||||
| MAP1743c | Rv2032 | Conserved hypothetical protein | |||||
| MAP1744 | Hypothetical protein | ||||||
| 3 | 2608297 | 2609525 | 1,229 | MAP2325 | Rv2416c | Enhanced intracellular survival protein |
a
Par, partial.
b
CoA, coenzyme A; ACP, acyl carrier protein.