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British Journal of Clinical Pharmacology logoLink to British Journal of Clinical Pharmacology
. 1978 Feb;5(2):127–129. doi: 10.1111/j.1365-2125.1978.tb01612.x

The metabolic effects of inhaled salbutamol.

S M Bateman, J Pidgeon, S G Spiro, A J Johnson
PMCID: PMC1429254  PMID: 339934

Abstract

1 The metabolic effects of salbutamol (5 mg) given by intermittent positive pressure breathing have been studied in eight patients with airflow obstruction. 2 No changes in plasma nonesterified fatty acids, triglyceride, glucose, insulin or cortisol were seen 1 and 4 h after administration. 3 It is concluded that inhaled salbutamol does not cause the unwanted metabolic effects reported with oral or parenteral administration, and that this is a further indication for this route of administration.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Carruthers M., Young D. A. Free fatty acid estimation by a semi-automated fluorimetric method. Clin Chim Acta. 1973 Dec 27;49(3):341–348. doi: 10.1016/0009-8981(73)90231-3. [DOI] [PubMed] [Google Scholar]
  2. Choo-Kang Y. F., Grant I. W. Comparison of two methods of administering bronchodilator aerosol to asthmatic patients. Br Med J. 1975 Apr 19;2(5963):119–120. doi: 10.1136/bmj.2.5963.119. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Cramp D. G., Robertson G. The fluorometric assay of triglyceride by a semiautomated method. Anal Biochem. 1968 Oct 24;25(1):246–251. doi: 10.1016/0003-2697(68)90097-3. [DOI] [PubMed] [Google Scholar]
  4. Goldberg R., van As M., Joffe B. I., Krut L., Bersohn I., Seftel H. C. Metabolic responses to selective beta-adrenergic stimulation in man. Postgrad Med J. 1975 Feb;51(592):53–58. doi: 10.1136/pgmj.51.592.53. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Oliver M. F. Metabolic response during impending myocardial infarction. II. Clinical implications. Circulation. 1972 Feb;45(2):491–500. doi: 10.1161/01.cir.45.2.491. [DOI] [PubMed] [Google Scholar]
  6. Taylor M. W., Gaddie J., Murchison L. E., Palmer K. N. Metabolic effects of oral salbutamol. Br Med J. 1976 Jan 3;1(6000):22–22. doi: 10.1136/bmj.1.6000.22. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Tickner T. R., Cramp D. G., Foo A. Y., Johnson A. J., Bateman S. M., Pidgeon J., Spiro S. G., Clarke S. W., Wills M. R. Metabolic response to intravenous salbutamol therapy in acute asthma. Thorax. 1977 Apr;32(2):182–184. doi: 10.1136/thx.32.2.182. [DOI] [PMC free article] [PubMed] [Google Scholar]

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