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Gadd34-null mice manifest erythrocyte abnormalities. Blood smears of erythrocytes from wild-type and Gadd34-null mice stained with eosin Y, azure A, and methylene blue under ×1,000 magnification. Gadd34-null mouse erythrocytes show weaker staining (decreased hemoglobin) and general erythrocyte morphological abnormalities. A target cell is marked by an arrowhead, a Howell-Jolly body by an arrow, and a spiculocyte by a double arrow.
