FIG. 7.

Gadd34-null mice recover slowly from iron deficiency. Wild-type and Gadd34-null weanlings were placed on a basal or iron-deficient diet. Mice on the iron-deficient diet were returned to the basal diet after 8 weeks (designated by arrows). Slopes (m) for MCV and MCH were calculated from the best-fit line of values from weeks 8 through 14. Data for wild-type (basal diet, five males and two females; iron-deficient diet, six males and three females) and Gadd34-null (basal diet, three males and three females; iron-deficient diet, four males and four females) mice are presented as averages of all values for each genotype and parameter ± standard errors of the mean. P values were calculated by ANOVA. RBC, red blood cell.