TABLE 1.
Hematologic parameters of Gadd34-null mice
| Parametera | Mean value ± SEM for mice:
|
Pb | |
|---|---|---|---|
| Wild type (n = 8) | Gadd34 null (n = 9) | ||
| Hematocrit | 41.9 ± 1.3 | 40.9 ± 0.9 | NS |
| Hb (g/dl) | 12.9 ± 0.3 | 11.0 ± 0.3 | 0.0004 |
| RBC (106/μl) | 8.7 ± 0.2 | 10.8 ± 0.3 | <0.0001 |
| MCHC (g/dl) | 30.9 ± 1.0 | 28.9 ± 1.0 | 0.0013 |
| MCV (fl) | 47.8 ± 1.5 | 38.2 ± 1.0 | <0.0001 |
| RDW (%) | 17.0 ± 0.2 | 23.7 ± 0.4 | <0.0001 |
a
Hb, hemoglobin. RBC, red blood cell. MCHC, mean corpuscular hemoglobin content. RDW, RBC distrubution width.
b
P values were calculated with an unpaired t test. NS, not significant.