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. Author manuscript; available in PMC: 2006 Apr 5.
Published in final edited form as: Nat Med. 2005 May 22;11(7):774–779. doi: 10.1038/nm1255

Figure 4. Osteoclasts generated from CB1 KO mice are resistant to the inhibitory effects of CB1 selective, but not CB2 selective receptor antagonists.

Figure 4

a, effect of AM251 on osteoclast formation in RANKL / M–CSF stimulated bone marrow cultures prepared from CB1 KO mice and wild type littermates. b, effect of AM630 on osteoclast formation in bone marrow mononuclear cells cultured from wild type and CB1 KO mice. Values are means and standard deviations. Significant differences from control cultures are indicated by * p<0.05. Significant differences between CB1 KO and wild type cultures are indicated by # p<0.05.