Table 5.
HLA-DR molecules carried by responders and nonresponders to each gp43 peptide selected by TEPITOPEa
| HLA-DR
|
||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 4 | 7 | 8 | 9 | 10 | 11 | 13 | 14 | 15 | 16 | 17 | Blank | Responseb | ||
| gp43(45-59) | Responder | 2 | 2 | 1 | 1 | 1 | 2 | 1 | 2 | 2 | 10/11 | |||
| Nonresponder | 1 | 4 | 1 | 2 | 2 | |||||||||
| gp43(94-108) | Responder | 2 | 1 | 2 | 1 | 1 | 4 | 1 | 1 | 2 | 1 | 10/11 | ||
| Nonresponder | 3 | 1 | 3 | 1 | 1 | 2 | 1 | |||||||
| gp43(106-120) | Responder | 2 | 2 | 1 | 1 | 3 | 2 | 1 | 7/11 | |||||
| Nonresponder | 4 | 1 | 3 | 1 | 1 | 2 | 2 | 1 | ||||||
| gp43(180-194) | Responder | 2 | 3 | 2 | 1 | 4 | 1 | 2 | 3 | 10/11 | ||||
| Nonresponder | 3 | 1 | 1 | 2 | ||||||||||
| Gp43(283-298) | Responder | 2 | 1 | 1 | 3 | 1 | 3 | 1 | 7/11 | |||||
| Nonresponder | 4 | 1 | 2 | 4 | 1 | 2 | 1 | 1 | ||||||
a
Results are among the 14 PCM patients that responded to at least 1 peptide.
b
Response = number of HLA-DR molecules associated with response.