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. 2003 Sep-Dec;9(9-12):193–199. doi: 10.2119/2004-00002.johansson

Figure 5.

Figure 5

Urinary PBG levels following repeated subcutaneous injections of recombinant human PBGD (rhPBGD). PBGD-deficient mice were administered daily intraperitoneally with increasing doses of phenobarbital (75 to 90 mg/kg) for 4 d at 2 occasions (days 1 to 4 and days 8 to 11). The arrows indicate time of phenobarbital (PB) as well as rhPBGD administration. One mouse was administered subcutaneously with rhPBGD twice daily (20 mg/kg) between days 1 and 5. Urine was collected in 24-h fractions and PBG concentrations were expressed as mmol/mol creatinine.