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. 2004 Jan-Jun;10(1-6):28–35. doi: 10.2119/2004-00001.szabo

Figure 4.

Figure 4

Pharmacological inhibition of PARP with PJ34 prevents (A) or improves (B) the AII-induced endothelial dysfunction. Acetylcholine-induced endothelium-dependent relaxations are shown. Each point of the curve represents mean ±SEM of 6 to 8 experiments in vascular rings. *P < 0.05 compared with control (CO) and †P < 0.05 compared with AII. Animals receiving AII were treated with PJ34 (30 mg/kg/d) from day 0 (A: n = 8) or d 7 (B: n = 6) following AII-releasing minipump implantation for 1 wk.