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. 2006 Mar 9;7:21. doi: 10.1186/1471-2350-7-21

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Copyright © 2006 Szyld et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Map of the investigated HLA region with p values of the markers used in the initial screen. Figure shows the investigated fragment of chromosome 6 comprising the previously defined WG associated region encompassing the HLA-DPB1 and RXRB genes. Vertical lines represent studied microsatellites. The lengths/heights of these lines correspond to p values after analyses in the initial screen with pooled DNA. The 4 markers, which were genotyped individually, are labelled. The p values of markers #1.0.0.1, #1.0.0.5 and #1.0.4.1 (pool analysis) could not be replicated by genotyping individually. Drawn in red is the marker (#1.0.3.7) that remained significantly different after individual genotyping. This marker has been used as a positive control (see text). For further information of fine localisation of each investigated marker and inter-marker distances see additional file 1.