Table 1.

Data estimates used for the analysis

Baseline assumptions		Reference
Prevalence of Group A Streptococcal infection based on population prevalence of 10% and Centor Score Score = 1	3%	3
Score = 2	8 %
Score = 3	19%
Score = 4	41%
Sensitivity of rapid streptococcal antigen test	84%	16
Specificity of rapid streptococcal antigen test	93%	16
Sensitivity of throat culture	78%	16
Specificity of throat culture	99%	16
Risk of penicillin rash	2%	17
Risk of anaphylaxis from oral penicillin	1/10,000	17
Risk of rheumatic fever if untreated	5/10,000	5, 15
Risk of rheumatic fever if treated	15/100,000	5, 15
Risk of peri-tonsillar abscess, if untreated	24/1,000	5, 15
Risk of peri-tonsillar abscess if treated	4/1,000	5, 15