Table 2.

K_m of PDEs

PDE	cAMP (μM)	cGMP (μM)	Refs
LmPDEB1	0.99	---	*)
LmPDEB2	6.98	---	*)
TbrPDEB1/TbPDE2C	7.97	---	[20]
TbrPDEB2/TbPDE2B	2.4	---	[21]
HsPDE1A1	112.7	5.0	[38]
HsPDE1B1	24.3	2.7	[38]
HcPDE1C2	1.2	1.1	[38]
HsPDE2	30 – 50	15 – 30	[38]
HsPDE3	0.1–0.8	0.1– 0.8	[38]
HsPDE4	1 – 3	---	[38]
HsPDE5	> 300	1 – 5	[38]
HsPDE6	910	14	[39]
HsPDE7	0.2 – 1	---	[38]
HsPDE8	0.06 – 0.15	124	[38]
HsPDE9	320	0.007–0.17	[38]
HsPDE10	0.05	3	[38]
HsPDE11	0.5	1	[38]

*) this work