Table 1.
Characteristics | Patients |
Entered | n = 54 |
Age median (years) (range) | 46 years (range 25 – 73 y) |
Estrogen receptor/progesterone receptor positive | 23/15 |
HERcepTest+++/FISH+ | 51/3 |
primary metastatic disease | 12 (22.2%) |
Metastatic sites median (range) | 3 (range 1–7 sites) |
Lung | 22 |
Liver | 29 |
Bones | 30 |
Lymph nodes | 22 |
Soft tissue | 36 |
Skin | 11 |
Brain | 11 |
Others | 3 |
More than one metastatic site | 48 (88.8%) |
Adjuvant chemotherapy | 31 (57.4%) |
Adjuvant docetaxel | 13 |
Adjuvant anthracyclines | 19 |
Adjuvant endocrine therapy | 15 (27.7%) |
Palliative endocrine therapy | 20 (37%) |
1st line combination | n = 54 pts |
Vinorelbine | 35 |
Capecitabine | 2 |
Gemcitabine | 0 |
Docetaxel | 12 |
Platinum derivatives | 0 |
Others | 5 |
2nd line combination | n = 54 pts |
Vinorelbine | 15 |
Capecitabine | 11 |
Gemcitabine | 9 |
Docetaxel | 11 |
Platinum derivatives | 0 |
Others | 8 |
Beyond 2nd line combination | n = 60 therapies |
Vinorelbine | 6 |
Capecitabine | 14 |
Gemcitabine | 14 |
Docetaxel | 4 |
Platinum derivatives | 11 |
Others | 11 |