Reference |
Population |
Results/Conclusions |
Brouwer et al., 1996 [19] |
95 pts with HF, HRV and Poincaré plots from 24 hr holter recordings (Ibopamine Multicenter Trial study group) |
Shape of Poincaré plots independent prognostic value in pts with mild to moderate HF |
Bigger et al., 1996 [2] |
(1) 715 pts with recent MI
(2) 274 healthy pts
(3) 19 pts with heart transplant
(Multicenter Post Infarction Program) |
MI or denervation of the heart causes a steeper slope and ↓ height of power law slope |
Huikuri et al., 1999 [10] |
446 with MI with ↓ LV function (EF<35%)
F/U 685±360 days |
Alpha-1 is the most powerful predictor of all cause mortality |
Huikuri et al., 1998 [7] |
Random sample of 347 patients of >65 yrs
F/U for 10 yrs |
Power law slope is a more powerful predictor of death than the traditional risk markers in elderly subjects |
Kamen et al, 1995 [21] |
Poincaré plot pattern to display beat to beat HRV data from 23 pts with HF and compared with 20 healthy people |
Poincaré plot is a semi-quantitative tool which can be applied to the analysis of R-R interval |
Laitio et al., 2002 [22] |
HRV and Poincaré plots of 40 pts with CABG |
SD1/SD2 ratio is the most powerful independent predictor of postoperative ischaemia |
Laitio et al., 2004 [13] |
32 pts aged ≥60 yrs admitted to hospital for surgical repair of traumatic hip fracture |
Alpha-1 predicts post operative myocardial infarction |
Lombardi et al.1996 [8] |
HRV in 2 groups of pts after MI (normal and reduced LVEF). Group1: 20 pts; Group 2: 15 pts |
Steeper slope of the negative regression line between power and frequency among reduced LVEF |
Mäkikallio et al., 1998 [23] |
38 pts with stable angina without previous MI or cardiac medication and 38 age matched healthy pts |
Alpha-1 helps differentiate CAD and healthy pts |