TABLE 2.
Virulence of SPI-2 mutant Salmonella serovar Typhimurium for mice
| Strain 1 genotype | Strain 2 genotype | Log10 competitive indexa (strain 1/strain 2) |
|---|---|---|
| Wild typeb | Wild typec | 0.00 ± 0.09 |
| ssaT | Wild typec | −2.32 ± 0.18 |
| ΔsifA | Wild typec | −1.11 ± 0.14 |
| ΔsseJ | Wild typec | −0.32 ± 0.15 |
| ΔsifB | Wild typec | −0.08 ± 0.06 |
| ΔsifA ΔsifB | Wild typec | −1.00 ± 0.12 |
| ΔsifA ΔsseJ | Wild typec | −1.44 ± 0.17 |
| ΔsseJ ΔsifB | Wild typec | −0.31 ± 0.11 |
| ssaT | ΔsifA | −1.39 ± 0.19 |
| ΔsifA ΔsseJ | ΔsifA | −0.36 ± 0.09 |
a
Ratio of the numbers of strain 1 to strain 2 bacteria recovered from infected spleens removed 2 days after the intraperitoneal injection of 105 total bacteria into mice. The mean competitive index from the infection of at least four mice is reported with the corresponding standard deviation.
b
Wild-type chloramphenicol-resistant strain CS401, parent strain for all mutant strains.
c
Wild-type kanamycin-resistant strain CS600, isogenic to CS401.