Figure 3.

Time course of gene expression in wild type (S), parental (P), and rpb1-1 mutant (M) stationary phase cultures exposed to 50 μM menadione for 0, 2, and 30 minutes. Heat map of results from unsupervised hierarchical clustering (Pearson's centered, average-linkage). Approximately 1,000 transcripts were included in this analysis. Samples were taken at T₀, T₂, and T₃₀ minutes after exposure to 50 μM menadione. The color scale at the bottom indicates the log₂ values for changes in mRNA abundance.