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. Author manuscript; available in PMC: 2006 Apr 6.
Published in final edited form as: Alcohol Clin Exp Res. 2005 Aug;29(8):1496–1503. doi: 10.1097/01.alc.0000174691.03751.11

Table 1.

Pathological Features of CHOP (+/+ vs -/-) Mice Fed Ethanol

Genotype
 CHOP (+/+)
 CHOP (-/-)
Treatment Control (n = 3) Ethanol (n = 4) Control (n = 4) Ethanol (n = 4)
Liver/body 0.053 ± 0.001 0.071 ± 0.002* 0.056 ± 0.004 0.067 ± 0.003*
Steatosis score 0.17 ± 0.03 2.5 ± 0.58* 0.13 ± 0.25 2.1 ± 0.25*
Triglycerides (mg/mg protein) 0.065 ± 0.016 0.305 ± 0.019* 0.052 ± 0.010 0.29 ± 0.018*
ALT (U) 14 ± 0.6 112 ± 14* 13 ± 1.7 87 ± 37*
Hcy (μM) 2.6 ± 0.75 18.3 ± 1.93 2.9 ± 0.22 17.3 ± 3.65*
Necroinflammatory foci1 0 0.5 ± 0.6* 0 0.3 ± 0.5*
Apoptotic nuclei2 0.3 ± 0.6 5.5 ± 1.3* 0 0
1

number of necrotic foci counted in five microscope fields of each section of liver tissue with x200 original magnification.

2

number of apoptotic nuclei counted in five microscope fields of each section of liver tissue with x200 original magnification.

*

p < 0.05 compared to control.