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. Author manuscript; available in PMC: 2006 Sep 1.
Published in final edited form as: Mol Cancer Ther. 2005 Sep;4(9):1349–1357. doi: 10.1158/1535-7163.MCT-05-0149

Figure 3. Effect of PX-866 on plasma insulin and glucose tolerance.

Figure 3

A, Plasma insulin in female C57Bl/6 mice fasted for 16 hr. (○) vehicle control and (•) mice administered PX-866 10 mg/kg po. Values are the mean of 3 mice and bars are SE. B, Plasma glucose in female C57Bl/6 mice fasted for 16 hr and administered a dose of glucose of 1 g/kg po. (○) vehicle control; (•) administered PX-866 10 mg/kg 4 hr previously; (_) treated daily for 7 days with pioglitazone 10 mg/kg ip; and (Δ) treated daily for 7 days with pioglitazone 10 mg/kg ip and administered PX-866 10 mg/kg 4 hr previously. Values are the mean of 4 mice and bars are SE.