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. 2003 Jan;71(1):47–60. doi: 10.1128/IAI.71.1.47-60.2003

FIG. 1.

FIG. 1.

Map of the UCS-MSG locus and locations of PCR primers. The UCS region of the locus is invariant and marks a unique telomeric site in the genome. Adjacent to the UCS, there is always a sequence encoding a protein called MSG. The MSG gene sequence at the UCS locus can be different in different organisms, presumably because recombination installs different MSG-encoding sequences at the UCS locus. The genome carries many copies of MSG-encoding sequences, which reside at the ends of all chromosomes and differ from one another. Only the MSG-encoding sequence that is linked to the UCS locus is represented by mRNA. The CRJE is a 25-bp conserved sequence located between the UCS and its adjacent MSG gene. A copy of the CRJE is also at the beginning of all known MSG-encoding sequences not attached to the UCS locus.