TABLE 4.
Relative Energies of the Salt–Bridge Isomer of Bradykinin (IV) Calculated at the MMFF and EDF1 Density Functional Levelsa
conformer | rel energy (MMFF) (kcal/mol) | EDF1//MMFF energy (hartrees) | rel energy (EDF1//MMFF) (kcal/mol) |
---|---|---|---|
1 | 0.0 | −3599.003 735 | 0 |
2 | 1.2 | −3598.996 902 | 4.3 |
3 | 4.0 | −3599.006 408 | −1.7 |
4 | 4.7 | −3599.006 158 | −1.5 |
5 | 5.0 | −3599.000 186 | 2.2 |
6 | 5.7 | −3598.997 043 | 4.2 |
7 | 9.3 | −3598.986 379 | 10.9 |
The total and relative energies at the EDF1 level (6-31G* basis) are calculated using MMFF geometries.