Table 2.
Comparison of our system (GOPET) with the annotation systems GOtcha and GOFigure to predict the molecular function for eight Xenopus leavis sequences. Basically, the first four hits are shown, for GOPET and GOtcha with confidence values ≥ 80%.
| GOPET | GOtcha | GOFigure | ||||||
| Contig | GO ID | Confidence | GO term | GO ID | Estimated likelihood | GO term | GO ID | GO term |
| TC212171 | 0008233 | 100% | peptidase activity | 0003824 | 98% | enzyme activity | 0004263 | chymotrypsin activity |
| 0004175 | 100% | endopeptidase activity | 0008233 | 98% | peptidase activity | 0004295 | trypsin activity | |
| 008236 | 98% | serine-type peptidase activity | 0016787 | 98% | hydrolase activity | |||
| 0016787 | 98% | hydrolase activity | 0008236 | 98% | serine-type peptidase activity | |||
| TC196381 | 004175 | 100% | endopeptidase activity | 0003824 | 93% | enzyme activity | 0004263 | chymotrypsin activity |
| 0016787 | 98% | hydrolase activity | 0004295 | trypsin activity | ||||
| 0008233 | 98% | peptidase activity | ||||||
| 0008236 | 97% | serine-type peptidase activity | ||||||
| TC209487 | 0003824 | 100% | enzyme activity | 0003824 | 90% | enzyme activity | 0004177 | aminopeptidase activity |
| 0016787 | 100% | hydrolase activity | 0004301 | epoxide hydrolase activity | ||||
| 0004177 | 90% | aminopeptidase activity | ||||||
| 0017171 | 85% | serine hydrolase activity | ||||||
| TC187949 | 0004888 | 100% | transmembrane receptor activity | 0004872 | 93% | receptor activity | 0004888 | transmembrane receptor activity |
| 0004872 | 97% | receptor activity | 0004888 | 93% | transmembrane receptor activity | |||
| 0004871 | 93% | signal transducer activity | ||||||
| 0004930 | 93% | G-protein coupled receptor activity | ||||||
| TC194305 | 0003824 | 100% | enzyme activity | - | - | - | 0004674 | protein serine/threonine kinase activity |
| 0016740 | 99% | transferase activity | 0005524 | ATP binding | ||||
| 0016301 | 99% | kinase activity | ||||||
| 0004672 | 97% | protein kinase activity | ||||||
| TC210151 | 0004872 | 100% | receptor activity | 0004872 | 98% | receptor activity | 0004926 | non-G-protein coupled 7TM receptor activity |
| 0004888 | 97% | transmembrane receptor activity | 0004871 | 98% | signal transducer activity | 0004930 | G-protein coupled receptor activity | |
| 0004928 | 82% | frizzled receptor activity | 0004888 | 98% | transmembrane receptor activity | |||
| 0004930 | 98% | G-protein coupled receptor activity | ||||||
| 0004926 | 92% | non-G-protein coupled 7TM receptor activity | ||||||
| 0004928 | 80% | frizzled receptor activity | ||||||
| TC199713 | 0004602 | 100% | glutathione peroxidase activity | 0003824 | 99% | enzyme activity | 0004601 | peroxidase activity |
| 0016491 | 98% | oxidoreductase activity | 0004601 | 99% | peroxidase activity | 0004602 | glutathione peroxidase activity | |
| 0004601 | 85% | peroxidase activity | 0016491 | 99% | oxidoreductase activity | |||
| 0016684 | 99% | oxidoreductase, acting on peroxide as acceptor activity | ||||||
| 0004602 | 97% | glutathione peroxidase activity | ||||||
| TC190605 | 0003824 | 100% | enzyme activity | 0003824 | 92% | enzyme activity | 0004518 | nuclease activity |
| 0016787 | 100% | hydrolase activity | ||||||
| 0017171 | 87% | serine hydrolase activity | ||||||