Table 1.

All adverse events by dose levels

Dose levela	Type	No. of events	Toxicity gradeb
1000 mg	Diarrhea	1	1
4000 mg	Headache	1	1
8000 mg	Rash	1	1
	Yellow Stool	1	1
10000 mg	Yellow Stool	1	1
	Headache	1	1
12000 mg	Diarrhea	1	1

^a Total of 3 subjects at each dose level

^b National Cancer Institute, Common Toxicity Criteria v.2.0 [10]