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. Author manuscript; available in PMC: 2006 Apr 10.
Published in final edited form as: Mol Microbiol. 2006 Feb;59(4):1317–1326. doi: 10.1111/j.1365-2958.2005.05012.x

Fig. 4.

Fig. 4

Differentiating between intra- and inter-subunit signal transduction. A. Complementation assays were performed as described in the legend to Fig. 3, except swarm plates were incubated for 24 h. The Aer-N34DM1 + Aer-Q248R/M341TM2 heterodimer and the Aer-N34D/M341TM1 + Aer-Q248RM2 heterodimer were non-aerotactic and aerotactic respectively, supporting a signalling pathway within one subunit. B. Cartoons of Aer heterodimers showing missense mutations (X). An intra-subunit signalling pathway is indicated by a continuous arrow, and a defective signalling pathway by a blocked arrow. A shaded PAS domain (circle) denotes FAD binding.