Table 4.
Estrogen Plus Progestin Arm of the Women's Health Initiative -- Changes in Quality of Life in Change in Estrogen Plus Progestin Minus Change in Placebo [32]
| Positive Effect |
Negative Effect |
Smallest Increment of Change* |
Standard Deviation in Placebo* |
|
|---|---|---|---|---|
| General health | + 1 | + 5 | + 14 | |
| Physical functioning | + 2 | + 5 | + 15 | |
| Role limitations due to physical problems | + 3 | +25 | + 35 | |
| Bodily pain | + 4 | + 13 | + 22 | |
| Energy and fatigue | + 0.2 | + 7 | +16 | |
| Social functioning | 0 | 0 | - 12 | - 19.5 |
| Role limitations due to emotional problems | 0 | 0 | - 33 | - 31 |
| Mental health | 0 | 0 | - 12 | - 12 |
| Modified Mini-Mental State Examination | 0 | 0 | + 2 | + 5 |
| Depression – continuous variable | 0 | 0 | ND | - 22 |
| Sleep disturbances | + 4 | + 5 | + 20 | |
| Satisfaction with sex | + 2 | + 34 | + 37 |
*The numerical data were extrapolated from the WHI paper since numerical data was not stated.[32]