Figure 3.

Distribution of plasma antibodies levels (in arbitrary units, AU) to EBA-175 peptide 4 in children who had clinical malaria (unprotected = NP) and those who had an asymptomatic infection (protected = P). (A) total IgG, (B) IgG1, (C) IgG2, (D) IgG3, (E) IgG4. The 10^th, 25^th, 75^th and 90^th percentile boxes for the AU values of each IgG subclass are presented and the horizontal line within these percentile boxes indicate the median AU. There were significant differences in the distributions of total IgG and IgG1 levels between both groups of children (Mann-Whitney U test, P = 0.009 and 0.043, respectively).