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. 2006 Apr 14;2(4):e28. doi: 10.1371/journal.ppat.0020028

Figure 6. Histopathology of Mouse Lymph Nodes.

Figure 6

(A) Normal lymph node architecture of a gp91phox−/− uninjected control mouse (magnification 5×).

(B) Normal lymph node architecture of a gp91phox −/− mouse after 107 i.p. inoculation of Gluconobacter oxydans (magnification 5×).

(C) Moderate lymphoid hyperplasia and presence of atypical macrophages in the lymph node of a gp91phox −/− mouse after 106 intraperitoneal inoculation of the novel organism (magnification 5×).

(D) View of the epithelioid macrophages in the lymph node at 40×.

(E) Lymphadenitis in the cervical lymph node of a gp91phox −/− mouse after 107 i.p. inoculation of the novel organism (magnification 5×).

(F) View of the pyogranulomatous reaction in the lymph node at 20×.

(A,B,E,F) are from mice that were sacrificed at nine days post-inoculation. (C and D) are from a mouse that was sacrificed at 76 days post-inoculation.