Table 2.

Feed-forward and coherent loops statistics. The coherent loops were converted only if the relation between the transcription factor and a target was PromoterBinding. Table shows the number of loops with different relation types between the regulator node and the transcription factor node (Figure 1). Coherent loops are feed-forward loops with coherent regulation effects. Because many loops shared the same Expression relation between regulator and target, the number of Expression relations converted to regulation is smaller than the total number of coherent loops.

	Feed-forward loops		Coherent loops
Relation from Regulator to TF	Number of unique Expression relations	Number of loops	Number of unique Expression relations	Number of loops
DirectRegulation	3242	4849	1109	1345
Expression	8911	13468	3638	4600
MolSynthesis	231	233	95	96
PromoterBinding	591	767	124	133
Regulation	10592	17246	4359	5646
Total	26689	40588	7411	12023