Table 4.
Example candidate SNPs for hypertension
| RefSNP ID | Gene Name | Refseq Protein | SNP | SVM profile | SVM structure | Structure and Sequence Properties | dbSNP ID and Population Frequency |
| rs11571098 | REN | NP_000528 | R33W | -1.63 | -0.21 | Salt Bridge lost | ss20420843:4% (African American) |
| rs4976 | ACE | NP_690044 | I444T | -1.26 | -1.15 | Hydrophobic Interaction loss | ss6413:5% (Multination) [76] |
| rs5247 | CMA1 | NP_001827 | H66R | -2.51 | -1.49 | Salt Bridge lost; key catalytic residue, very conserved | ss6694:10% (Multination) [76] |
| rs5518 | KLK1 | NP_002248 | V193E | -1.62 | -0.70 | Buried Charge, hydrophobic interaction decreased | ss6984:5% (Multination) [76] |