FIG. 1.

The BKV VP1_p44 and VP1_p108 peptides are recognized by CTL from an HLA-A*0201⁺ healthy individual. Autologous and HLA-A*0201-matched only target cells sensitized with BKV VP1 peptides p44 AITEVECFL (a) or p108 LLMWEAVTV (b) were lysed by peptide-stimulated PBMC from a healthy study subject. No significant lysis was observed using fully MHC-I-mismatched target cells. The percentage of specific lysis indicates the difference in specific ⁵¹Cr release between target cells pulsed with the BKV VP1 peptides and those pulsed with the control peptide. Effector target (E:T) ratios are shown.