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CD analysis of inhibitor-bound gp120JRFL. The CD spectra of purified gp120JRFL and that treated with BMS-488043 were scanned with a Jasco J-720 Spectropolarimeter. (A) CD spectra with (dashed line) and without (solid line) the presence of BMS-488043. (B) Effect of BMS-488043 concentration on the CDmin wavelength shift.
