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BMS-488043 inhibition of WT versus ΔCT virion binding to sCD4. Virions (JRFL) were incubated with sCD4 (1 μg/ml) in the presence of various inhibitor concentrations. sCD4-bound virions were captured (anti-CD4 OKT4). The p24 level was determined and normalized to that of the no-inhibitor control.
