TABLE 2.
Effect of alteration of glycosylation pattern of PRRSV GP5 on the ability of the infectious virion to react with neutralizing antibodiesa
| Animal no. | Endpoint with PRRSV strain:
|
|||
|---|---|---|---|---|
| Wt PRRSV (FL-12) | FL-N34A | FL-N51A | FL-N34/51A | |
| 11404 | 1:32 | 1:256 | 1:256 | 1:32,768 |
| 11346 | 1:8 | 1:64 | 1:256 | 1:16,384 |
| 11457 | 1:16 | NDb | 1:128 | 1:2,048 |
| 11407 | 1:8 | ND | 1:64 | 1:2,048 |
Data are inverse endpoint dilutions showing neutralization. Animals were infected with 105 TCID50 of wt PRRSV FL12, and serum samples were taken 47 days postinfection.
ND, not determined.