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Cytotoxic activitya in response to Gag and Env in immunized macaques
| Group | Vaccine regimen | No of positive animals/total no. tested
|
|||
|---|---|---|---|---|---|
| Wk 28
|
Wk 54
|
||||
| Env (HIV- 1BH10) | Gag (SIVmac251) | Env (HIV- 1BH10) | Gag (SIVmac251) | ||
| A | vCP250 + vCP172 + gp120 | 1/6 | 0/6 | 0/6 | 0/6 |
| B | vCP1420 + vCP172 + gp140 | 2/6 | 0/6 | 2/6 | 0/6 |
| C | vCP1420 + vCP172 + gp140 simultaneously | 1/6 | 0/6 | 0/6 | 2/6 |
| D | vCP172 | 0/6 | 1/6 | 0/6 | 1/6 |
Only cytotoxic activity 10% above background was scored positive.
