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. 2006 Apr 20;116(5):1337–1345. doi: 10.1172/JCI27400

Figure 2. Electron micrograph images from combined heterozygous mice between Cd2ap and Fyn.

Figure 2

(A) Representative electron microscopic images showing normal foot process architecture in wild-type (left panel), Cd2ap+/– (middle panel), and Fyn+/– (right panel) podocytes. (B) Electron micrographs from proteinuric Fyn–/– mice revealed only some coarsening of the foot processes. (C and D) Fyn+/–Cd2ap+/– mice (C) and Fyn–/–Cd2ap+/– mice (D) exhibited foot process effacement in some but not all areas. Magnification, ×12,000.